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Invitrogen™ VCAM-1 (Soluble) Human ELISA Kit

For the quantitative detection of human sVCAM-1.

Brand:  Invitrogen™ BMS232TEN

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15591777

  • £2250.00 / Pack of 10


Estimated Shipment date
from Supplier 09-03-2020
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Includes: Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to human sVCAM-1
Conjugate Mixture containing Biotin-Conjugate anti-human sVCAM-1 monoclonal antibody mixed with Streptavidin-HRP
Human sVCAM-1 Standard lyophilized, 200ng/mL upon reconstitution
Control high, lyophilized
Control low, lyophilized
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
Substrate Solution (tetramethyl-benzidine)
Stop Solution (1M Phosphoric acid)
Blue-Dye
Green-Dye
Adhesive Films

Description

Description

VCAM-1 (vascular cell adhesion protein 1, CD106, INCAM-110) is a cell surface sialoglycoprotein expressed by cytokine activated endothelium. VCAM-1 has a number of functions including the regulation of leukocyte migration, leukocyte-endothelial cell adhesion and signal transduction and may play a role in a number of inflammatory diseases. VCAM-1 is distributed across non-leukocyte and leukocyte cells. VCAM-1 expression is reportedly correlated with adhesion of melanoma, Burkitt lymphoma, osteosarcoma, and kidney carcinoma but not colon carcinoma cells to endothelial cells which may determine the site of tumor metastasis. VCAM-1 is a member of the Ig superfamily of adhesion molecules, is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on unstimulated endothelial cells. VCAM-1 is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. VCAM-1 serves as a ligand for leukocyte integrin alpha-beta (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. VCAM-1 plays a role in tumor metastasis, and may also be involved in the development of atherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms of VCAM-1 have been described.
Specifications

Specifications

P19320
Biotin
7412
Pre-coated 96 well plate, Adhesive Plate Covers, Standard, Sample Diluent, Assay Buffer concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Controls
RUO
100 μL (1:50 prediluted)
2°C to 8°C
2 hr. 10 min.
CD106,INCAM-100
5.2%
HRP
Human
3.15-100 ng/mL
ELISA
Colorimetric Microplate Reader
ELISA Kit
0.6 ng/mL
Amniotic Fluid, 100 μL|Plasma, 10 μL|Serum, 10 μL|Supernatant, 100 μL
1 hr. 20 min.
Human
Vascular cell adhesion protein 1, CD106 antigen
3.1%
10 x 96 Tests
Supernatant
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For Research Use Only