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Invitrogen™ P-Selectin (Soluble) (CD62) Human ELISA Kit

Sandwich ELISA Kit

Brand:  Invitrogen™ BMS219-4TEN

Code : NEW

Additional Details : Weight : 0.23750kg

Product Code. 15591707

  • £2250.00 / Pack of 10


Estimated Shipment date
from Supplier 03-03-2020
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Includes: Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to human sP-selectin
HRP-Conjugate anti-human sP-selectin monoclonal antibody
Human sP-selectin Standard lyophilized, 80ng/mL upon reconstitution
Control high, lyophilized
Control low, lyophilized
Sample Diluent
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
Substrate Solution (tetramethyl-benzidine)
Stop Solution (1M Phosphoric acid)
Blue-Dye
Green-Dye
Adhesive Films

Description

Description

P-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type 1 transmembrane glycoprotein, and is one of the most commonly studied proteins that regulate cell rolling. P-selectin is stored in the Weibel-Palade bodies of endothelial cells, as well as in a-granules of platelets. From there, it can be rapidly brought to the cell surface after exposure to thrombin, histamine, complement 5a, Ca21 ionophores, or adenosine diphosphate. P-selectin protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. P-selectin plays an important role in adhesive processes between leucocytes and endothelial cells, and is a calcium dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens found on neutrophils and monocytes. P-selectin is constitutively expressed in inflammation and contributes to atherogenesis, thrombosis and tissue destruction. Clinically, P-selectin is used to distinguish heparin induced thrombocytopenia with and without thrombosis.
Specifications

Specifications

P16109
HRP
6403
Pre-coated 96 well plate, Standard, Sample Diluent, Assay Buffer concentrate, HRP-conjugated Detection Antibody, Wash Buffer, Chromogen, Stop Solution, Controls, Adhesive Plate Covers
RUO
10 μL
2°C to 8°C
2 hr. 30 min.
CD62,CD62P,GMP140,GRMP,LECAM3,PADGEM,PSEL
5.4%
HRP
Human
0.63-40.00 ng/mL
ELISA
Colorimetric Microplate Reader
ELISA Kit
0.20 ng/mL
Amniotic Fluid, 10 μL|Plasma, 10 μL|Serum, 10 μL|Supernatant, 10 μL
1 hr. 20 min.
Human
Granule membrane protein 140, PADGEM, CD62P
7.8%
10 x 96 Tests
Supernatant
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For Research Use Only