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Invitrogen™ CD26 (Soluble) Human ELISA Kit

For the quantitative detection of human sCD26.

Brand:  Invitrogen™ BMS235TEN

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15591787

  • £2250.00 / Pack of 10


Estimated Shipment
05-10-2020
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Includes: Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to human sCD26
Biotin-Conjugate anti-human sCD26 monoclonal antibody
Streptavidin-HRP
Human sCD26 Standard, 500ng/mL upon dilution
Sample Diluent
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
Substrate Solution (tetramethyl-benzidine)
Stop Solution (1M Phosphoric acid)
Blue-Dye
Green-Dye
Red-Dye
Adhesive Films

Description

Description

CD26 (dipeptidyl peptidase IV, DPP IV), adenosine deaminase (ADA) binding protein) is a homodimeric atypical serine protease belonging to the prolyl oligopeptidase family. CD26 is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti CD3-induced IL - 2 production. CD26 identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. Further, CD26 is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. Alterations in CD26 peptidase activity are characteristic of malignant transformation, and the enzymatic activity increases dramatically with tumor grade and severity. CD26 is expressed in various blood cell types, but also in cells that are histogenetically related to activated fibroblasts. Alterations in CD26 density have been reported on circulating monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.
Specifications

Specifications

P27487
Biotin
1803
ELISA Kit
7.3 ng/mL
Serum, 20 μL|Supernatant, 20 μL
1 hr. 20 min.
Human
Dipeptidyl peptidase IV, ADCP 2, ADABP, TP 103
4.6%
Human
HRP
15.6-500 ng/mL
ELISA
Pre-coated 96 well plate, Standard, Sample Diluent, Assay Buffer concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
RUO
20 μL
2°C to 8°C
4 hr. 10 min.
ADABP,ADCP2,CD26,DPPIV,TP103
9.1%
10 x 96 Tests
Supernatant
Colorimetric Microplate Reader
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