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Invitrogen™ sCD134/OX40 (Soluble) Human ELISA Kit

For the quantitative detection of human sCD134/OX40.

Brand:  Invitrogen™ BMS296

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Product Code. 15581897

  • £377.00 /


Estimated Shipment
29-09-2020
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Includes: Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to human sCD134/OX40
Biotin-Conjugate anti-human sCD134/OX40 monoclonal antibody
Streptavidin-HRP
Human sCD134/OX40 Standard lyophilized, 10ng/mL upon reconstitution
Sample Diluent
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
Substrate Solution (tetramethyl-benzidine)
Stop Solution (1M Phosphoric acid)
Blue-Dye
Green-Dye
Red-Dye
Adhesive Films

Description

Description

OX40 (CD134) is a member of the TNF-receptor superfamily, and has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that OX40 promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.OX40 is not constitutively expressed on resting naïve T cells, unlike CD28. OX40 is a secondary costimulatory molecule, expressed after 24 to 72 hours following activation. OX40L, a ligand of OX40, is also not expressed on resting antigen presenting cells. Expression of OX40 is dependent on full activation of the T cell; without CD28, expression of OX40 is delayed and expressed at lower levels.
Specifications

Specifications

P43489
Biotin
7293
ELISA Kit
1.8 pg/mL
Serum, 25 μL|Supernatant, 25 μL
1 hr. 20 min.
Human
OX 40L receptor, ACT 35
8%
Human
HRP
78-5,000 pg/mL
ELISA
Pre-coated 96 well plate, Adhesive Plate Covers, Standard, Sample Diluent, Assay Buffer concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Lysis Buffer, Chromogen, Stop Solution
RUO
25 μL
2°C to 8°C
3 hr. 10 min.
ACT35,CD134,IMD16,OX40,TXGP1L
12%
96 Tests
Supernatant
Colorimetric Microplate Reader
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For Research Use Only