Invitrogen™ eBioscience™ Human IL-6, Recombinant Protein
Human Recombinant Protein
Brand: Invitrogen™ 14-8069-62
Code : NEW
Additional Details : Weight : 0.50000kg
DescriptionHuman IL-6 (also known as B Cell Stimulating Factor BCSF, BSF-2) is a ∽21-28 kDa factor produced by a variety of cell types including monocytes, fibroblasts and endothelial cells. Upon stimulation, macrophages, T, B, mast, glial cells, eosinophils, keratinocytes and granulocytes also secrete IL-6. This pleiotrophic cytokine influences antigen-specific immune response, inflammatory response, and the development of neurons and is a major mediator of the acute phase reaction.
|Sterile liquid; 10mM sodium phosphate, pH 7.2, 150mM NaCl, 0.5% BSA. 0.22μm filtered.|
|E. coli expressed amino acids Pro 29-Met 212 of mature human IL-6 accession # AF372214|
|Measured by human TF-1 cell proliferation assay. The ED50 is 0.1ng/mL, corresponding to a specific activity of 1.0 x 107 Units/mg.|
|The methionylated N-terminal protein has a predicted molecular mass of 21,041. The DTT-reduced and non-reduced protein migrate as 16kDa polypeptides on SDS-PAGE.|
|Less than 0.01ng/μg cytokine as determined by the LAL assay.|
For Research Use Only.