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Invitrogen™ eBioscience™ Human IL-6, Recombinant Protein

Human Recombinant Protein

Brand:  Invitrogen™ 14-8069-62

Code : NEW

Additional Details : Weight : 0.50000kg

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Product Code. 15102079

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Description

Description

Human IL-6 (also known as B Cell Stimulating Factor BCSF, BSF-2) is a ∽21-28 kDa factor produced by a variety of cell types including monocytes, fibroblasts and endothelial cells. Upon stimulation, macrophages, T, B, mast, glial cells, eosinophils, keratinocytes and granulocytes also secrete IL-6. This pleiotrophic cytokine influences antigen-specific immune response, inflammatory response, and the development of neurons and is a major mediator of the acute phase reaction.
Specifications

Specifications

AF372214
Sterile liquid; 10mM sodium phosphate, pH 7.2, 150mM NaCl, 0.5% BSA. 0.22μm filtered.
IL-6
>98%
E. coli
E. coli expressed amino acids Pro 29-Met 212 of mature human IL-6 accession # AF372214
Interleukin-6, IL6
Measured by human TF-1 cell proliferation assay. The ED50 is 0.1ng/mL, corresponding to a specific activity of 1.0 x 107 Units/mg.
Human
Cytokine Bioassays
The methionylated N-terminal protein has a predicted molecular mass of 21,041. The DTT-reduced and non-reduced protein migrate as 16kDa polypeptides on SDS-PAGE.
SDS-PAGE
5μg
RUO
Less than 0.01ng/μg cytokine as determined by the LAL assay.
FA
Unlabeled
Yes
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