Invitrogen™ eBioscience™ Human IFN beta, Recombinant Protein, Carrier-Free
Human Recombinant Protein
Brand: Invitrogen™ 34-8699-82
Code : NEW
Additional Details : Weight : 0.09500kg
DescriptionHuman interferon beta is a glycosylated member of the type I family of interferons, which also includes IFN alpha. Human IFN alpha and beta share 50% amino acid sequence homology and bind the IFN a/b receptor (IFNAR), which consists of two subunits IFNAR1 and IFNAR2, with different affinities. Binding of IFN to its receptor activates signal transduction, including the JAK/STAT and p38 MAPK pathways. Many studies have established IFN beta as a mediator of anti-viral, anti-proliferative, and anti-inflammatory functions, as well as an effective treatment for multiple sclerosis.
|SDS-PAGE and HPLC|
|Store lyophilized protein at less than or equal to -20°C. Reconstituted protein solution can be stored with carrier protein (e.g., 0.1% BSA) at less than or equal to -20°C.|
|CHO cells (amino acids Met22-Asn187; Accession # AAC41702.1)|
|The ED50 of this protein, as measured by stimulation of human TF-1 cell proliferation, is less than or equal to 0.1ng/mL, which corresponds to a specific activity of at least 1 x 107 units/mg.|
|Lyophilized from 10mM sodium citrate, 100mM sodium chloride, and 10mM sucrose|
|Less than 0.1ng/μg cytokine as determined by the LAL assay|
|Recombinant Protein, Carrier-Free|
For Research Use Only.