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Invitrogen™ IL-6 Human ELISA Kit

For the detection of human IL-6

Brand:  Invitrogen™ BMS213-2

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15571677

  • £377.00 / 96 tests


In stock, ready to ship: 18
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Includes: Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to human IL-6
Biotin-Conjugate anti-human IL-6 monoclonal antibody
Streptavidin-HRP
Human IL-6 Standard, lyophilized, 200pg/mL upon reconstitution
Control high
Control low
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
Substrate Solution (tetramethyl-benzidine)
Stop Solution (1M Phosphoric acid)
Blue-Dye
Green-Dye
Red-Dye
Adhesive Films

Description

Description

Interleukin 6 (IL-6) is a multifunctional 26 kD protein originally discovered in the medium of RNA-stimulated fibroblastoid cells. IL-6 appears to be directly involved in the responses that occur after infection and cellular injury, and it may prove to be important as IL-1 and TNF-a in regulating the acute phase response. IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages and endothelial cells. IL-6 acts upon a variety of cells including myeloid progenitor cells, T cells, B cells, and hepatocytes. In addition, IL-6 appears to interact with IL-2 in the proliferation of T lymphocytes. IL-6 potentiates the proliferative effect of IL-3 on multipotential hematopoietic progenitors. IL-6 plays a critical role in B-cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma. IL-6 is a very useful culture supplement for the generation of a high number of antibody-producing hybridomas. Primarily produced at sites of acute and chronic inflammation, IL-6 is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of IL-6 is implicated in a wide variety of inflammation-associated disease states including diabetes mellitus and systemic juvenile rheumatoid arthritis.
Specifications

Specifications

P05231
Biotin
3569
ELISA Kit
0.92 pg/mL
Plasma, 50 μL|Serum, 50 μL|Supernatant, 50 μL
1 hr. 20 min.
Human
Interferon-beta 2, B-cell stimulatory factor 2,HGF
3.4%
Human
HRP
1.56-100 pg/mL
ELISA
Pre-coated 96 well plate, Adhesive Plate Covers, Standard, Sample Diluent, Assay Buffer concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Controls, Chromogen, Stop Solution
RUO
50 μL
2°C to 8°C
3 hr. 10 min.
BSF-2,BSF2,CDF,HGF,HSF,IFN-beta-2,IFNB2,IL-6
5.2%
96 Tests
Supernatant
Colorimetric Microplate Reader
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For Research Use Only