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Human BMP-2 Carrier-Free, Recombinant Protein, eBioscience™

Recombinant Protein

Brand:  Affymetrix eBioscience 34-8507-85

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15568806

  • £999.02 / 500µg


Estimated Shipment date
from Supplier 26-07-2018
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Description

Description

BMP-2 is one of fifteen bone morphogenetic proteins (BMP) belonging to the TGF-beta superfamily. The BMPs were first identified as the active factors in demineralized bone matrix, with transcripts later being discovered in many other types of tissue. They are synthesized as large precursor molecules that must be cleaved into their active form and dimerize in order to exhibit functional activity. These dimers may include two identical or distinct BMP chains. BMP responsiveness appears to be limited to multipotent and immature cells. The BMPs are essential for osteogenesis and organogenesis during embryonic development, and also play a role in fracture and wound healing in adults. Applications Reported: Human BMP-2 Recombinant Protein Carrier-Free is biologically active. Applications Tested: The ED50 of this protein, as determined by alkaline phosphatase induction in C3H/10T1/2 cells, is 0.25-1μg/mL. This corresponds to a specific activity of 4x10e3 - 1x10e3 Units/mg. Source: E. coli expressed amino acids Gln283-Arg396 accession number NP_001191. Bioactivity: The ED50 of this protein, as determined by alkaline phosphatase induction in C3H/10T1/2 cells, is 0.25-1 ug/mL. This corresponds to a specific activity of 4x10e3 - 1x10e3 Units/mg. Endotoxin: Less than 0.01ng/ug cytokine as determined by the LAL assay. Purity: >97% as determined by SDS-PAGE. Molecular Weight: 13 kDa. Storage and handling: For best recovery, quick-spin vial prior to opening. Use in a sterile environment.
Specifications

Specifications

P12643
Cytokine Bioassays
protein with 0.1M glycine and no preservative; pH 3.0
13kDa
3.0
Affinity chromatography
E. coli
RUO
Recombinant
Human BMP-2 Carrier-Free
Control, Functional Assay
Recombinant Protein, Carrier-Free
Unlabeled
E. coli
0.5mg/mL
Liquid
650
Human BMP-2 Carrier-Free
SDS-PAGE
500μg
-80°C
E. coli expressed amino acids Gln283-Arg396 accession number NP_001191
Less than 0.01ng/μg cytokine as determined by the LAL assay.
BMP2
The ED50 of this protein, as determined by alkaline phosphatase induction in C3H/10T1/2 cells, is 0.25-1μg/mL. This corresponds to a specific activity of 4x103 - 1x103 Units/mg.
Human
Hu
Recombinant
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