eBioscience™ Human IL-2, Recombinant Protein

Human Recombinant Protein

Overview
Brand: eBioscience™

Manufacturer Part Number: 14-8029-81

50UG Human IL-2 Recombinant Protein

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15537486

Quantity Price
1 £ 483.6 / 50µg
Estimated Shipment date
from Supplier 13-12-2016
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Description and Specification

Specification

Conjugate Unlabeled
Cross Reactivity Human
For Use With (Application) Cytokine Bioassays
Formulation Sterile liquid: 40mM Acetate, 0.2M NaCl, pH 5, 1.0% BSA . 0.22μm filtered.
Molecular Weight 15kDa
Name IL-2
Purification Method SDS-PAGE
Purity >98%
Quantity 50μg
Recombinant Yes
Source E. coli
Regulatory Status RUO
Structural Form E. coli
Endotoxin Concentration Less than 0.01ng/μg cytokine as determined by the LAL assay.
Gene Symbol Interleukin-2
Validated Application FA
Biological Activity The ED50 of this protein, as measured by CTLL-2 proliferation assay, is less than or equal to 175pg/mL. This corresponds to a specific activity of greater than or equal to 5.7 x 106 Units/mg.

Human IL-2 (also known as TCGF) is a ∽15 kDa factor produced mainly by activated CD4+ T cells. IL-2 induces cell cycle progression of resting cells in an antigen non-specific manner and allows clonal expansion of activated T cells. IL-2 also acts on activated B cells, monocytes, NK, LAK cells, and on oligodendroglial cells in vitro. In addition, IL-2 plays a role in hematopoiesis, tumor surveillance and anti-inflammatory reactions and hence is a central regulator of the immune response. Non-glycosylated IL-2 is biologically active.