eBioscience™ Human IL-2, Recombinant Protein

Human Recombinant Protein

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-8029-63

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15527486

Quantity Price
1 £ 103.33 / 10µg
EU Stock 7
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Description and Specification

Specification

Molecular Weight 15kDa
Name IL-2
Cross Reactivity Human
Recombinant Yes
Endotoxin Concentration Less than 0.01ng/μg cytokine as determined by the LAL assay.
For Use With (Application) Cytokine Bioassays
Formulation Sterile liquid: 40mM Acetate, 0.2M NaCl, pH 5, 1.0% BSA . 0.22μm filtered.
Quantity 10μg
Validated Application FA
Biological Activity The ED50 of this protein, as measured by CTLL-2 proliferation assay, is less than or equal to 175pg/mL. This corresponds to a specific activity of greater than or equal to 5.7 x 106 Units/mg.
Purification Method SDS-PAGE
Source E. coli
Regulatory Status RUO
Structural Form E. coli
Gene Symbol Interleukin-2
Conjugate Unlabeled
Purity >98%

Human IL-2 (also known as TCGF) is a ∽15 kDa factor produced mainly by activated CD4+ T cells. IL-2 induces cell cycle progression of resting cells in an antigen non-specific manner and allows clonal expansion of activated T cells. IL-2 also acts on activated B cells, monocytes, NK, LAK cells, and on oligodendroglial cells in vitro. In addition, IL-2 plays a role in hematopoiesis, tumor surveillance and anti-inflammatory reactions and hence is a central regulator of the immune response. Non-glycosylated IL-2 is biologically active.