eBioscience™ Human TGF beta 2, Recombinant Protein, Carrier-Free

Human Recombinant Protein

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 34-8478-85

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Product Code. 15528806

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Description and Specification

Specification

Storage Requirements Store at less than or equal to -70°C.
Formulation Sterile liquid; 1mM Citrate, pH 3.5
Gene Symbol Transforming Growth Factor beta 2, TGFb2
Recombinant Yes
Product Type Recombinant Protein, Carrier-Free
Biological Activity The ED50 of this protein, as measured by inhibition of IL-4-dependent proliferation of mouse CTLL-2 cells is less than or equal to 1.5ng/mL. This corresponds to a specific activity of greater than or equal to 6.7 x 105 Units/mg.
Molecular Weight 25kDa
Concentration 0.5mg/mL
Quantity 500μg
Endotoxin Concentration Less than 0.1ng/μg cytokine as measured by LAL assay.
Cross Reactivity Human
Accession Number P61812
Name TGF beta 2
Source E. coli
Structural Form E. coli expressed, accession number P61812, N-terminal His-tag
Regulatory Status RUO
Purity >98%
Purification Method SDS-PAGE
Conjugate Unlabeled
For Use With (Application) Functional Assays

Human Transforming Growth Factor beta 2 (TGF beta 2) is a member of a superfamily of disulfide-linked homodimeric proteins secreted as latent proteins and stored at the cell surface and extracellular matrix. The bioactive TGF beta 2 is released from a latent complex by proteolytic processing and conformation changes. TGF beta 2 regulates cell proliferation, growth, differentiation and motility as well as synthesis and deposition of the extracellular matrix and is also involved in embryogenesis, tissue remodeling and wound healing.