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Invitrogen™ Fibronectin Human ELISA Kit

For the quantitative detection of human Fibronectin.

Brand:  Invitrogen™ BMS2028TEN

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15571517

  • £2250.00 / Pack of 10


Estimated Shipment
06-10-2020
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Includes: Aluminium pouch(es) with a Microwell Plate coated with polyclonal antibody to human Fibronectin
Biotin-Conjugate anti-human Fibronectin polyclonal antibody
Streptavidin-HRP
Human Fibronectin Standard lyophilized, 40ng/mL upon reconstitution
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
Substrate Solution (tetramethyl-benzidine)
Stop Solution (1M Phosphoric acid)
Blue-Dye
Green-Dye
Red-Dye
Adhesive Films

Description

Description

Fibronectin is a disulfide-bonded dimer with a molecular weight range of 230-250 kDa. In the extracellular matrix of several connective tissues and vessels, fibronectin is present as an insoluble protein that is extensively cross-linked by interchain disulfide bonds forming high molecular mass polymers. Fibronectin is most abundant during embryonic development and tissue remodeling. Fibronectin is also present at high concentrations as a soluble plasma protein. Fibronectin is organized as a linear series of repeating modules which form domains for interaction with fibronectin itself, other matrix components (e.g. collagen and heparin) and receptors on cells (e.g. integrins). Fibronectin is present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. Fibronectin has been implicated in carcinoma development in lung cancer. Further, Fibronectin expression is increased especially in non-small cell lung carcinoma. The adhesion of lung carcinoma cells to Fibronectin enhances tumorgenecity and confers resistance to apoptosis induced by standard chemotherapeutic agents. The gene encoding Fibronectin has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some Fibronectin variants has not been determined.
Specifications

Specifications

P02751
Biotin
2335
ELISA Kit
0.1 ng/mL
Plasma, 10 μL|Serum, 10 μL|Supernatant, 50 μL|Urine,50 μL
1 hr. 20 min.
Human
Cold insoluble globulin, FINC, LETS, MSF, FN
5.3%
Human
HRP
0.31-20.0 ng/mL
ELISA
Pre-coated 96 well plate, Standard, Sample Diluent, Assay Buffer concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
RUO
50 μL (1:10.000 prediluted)
2°C to 8°C
3 hr. 10 min.
CIG,ED-B,FINC,FN,FNZ,GFND,GFND2,LETS,MSF
6.7%
10 x 96 Tests
Urine
Colorimetric Microplate Reader
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