eBioscience™ Human TGF beta 2, Recombinant Protein, Carrier-Free

Human Recombinant Protein

Overview
Brand: eBioscience™

Manufacturer Part Number: 34-8478-82

100UG Human TGF beta 2 Recombinant Protein Carrier-Free

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Product Code. 15518806

Quantity Price
1 £ 1219.6 / 100µg
Estimated Shipment date
from Supplier 08-12-2016
Add to basket


Description and Specification

Specification

Accession Number P61812
Concentration 0.5mg/mL
Conjugate Unlabeled
Cross Reactivity Human
For Use With (Application) Functional Assays
Formulation Sterile liquid; 1mM Citrate, pH 3.5
Molecular Weight 25kDa
Name TGF beta 2
Purification Method SDS-PAGE
Purity >98%
Quantity 100μg
Recombinant Yes
Source E. coli
Storage Requirements Store at less than or equal to -70°C.
Regulatory Status RUO
Structural Form E. coli expressed, accession number P61812, N-terminal His-tag
Endotoxin Concentration Less than 0.1ng/μg cytokine as measured by LAL assay.
Gene Symbol Transforming Growth Factor beta 2, TGFb2
Biological Activity The ED50 of this protein, as measured by inhibition of IL-4-dependent proliferation of mouse CTLL-2 cells is less than or equal to 1.5ng/mL. This corresponds to a specific activity of greater than or equal to 6.7 x 105 Units/mg.
Product Type Recombinant Protein, Carrier-Free

Human Transforming Growth Factor beta 2 (TGF beta 2) is a member of a superfamily of disulfide-linked homodimeric proteins secreted as latent proteins and stored at the cell surface and extracellular matrix. The bioactive TGF beta 2 is released from a latent complex by proteolytic processing and conformation changes. TGF beta 2 regulates cell proliferation, growth, differentiation and motility as well as synthesis and deposition of the extracellular matrix and is also involved in embryogenesis, tissue remodeling and wound healing.