HLA-E Mouse anti-Human, Clone: 3D12HLA-E, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-9953-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15557836

Quantity Price
1 £ 140.02 / 100µg
EU Stock 2
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Description and Specification

Specification

Formulation aqueous buffer, no sodium azide
Conjugate Unlabeled
Host Species Mouse
Clone 3D12HLA-E
Species Reactivity Human
Isotype IgG1
Quantity 100μg
Antigen HLA-E
Primary or Secondary Primary
Applications Flow Cytometry
Applications Functional Assay
Concentration 1mg/mL
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Format Purified
Storage Requirements Store at 2-8°C.

The monoclonal antibody 3D12 (HLA-E) recognizes human HLA-E, a member of the Human Leukocyte Antigen family. HLA-E is a MHC Class IB member, which has a specialized role in NK cell recognition. Binding of a restricted set of peptides derived from other Class I leader sequences to the HLA-E and B2M (beta2 microglobulin) complex leads to interaction with NKG2A on NK cells. This binding protects the HLA-G-expressing cell from NK cell killing. HLA-E expression is ubiquitous.