HLA-E Mouse anti-Human, Clone: 3D12HLA-E, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9953-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15288267

Quantity Price
1 £ 66.65 / 25µg
EU Stock 1
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Description and Specification

Specification

Applications Flow Cytometry
Applications Immunoprecipitation
Applications Western Blotting
Primary or Secondary Primary
Isotype IgG1
Quantity 25μg
Monoclonal or Polyclonal Monoclonal
Format Purified
Storage Requirements Store at 2-8°C.
Antigen HLA-E
Concentration 0.5mg/mL
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Mouse
Species Reactivity Human
Clone 3D12HLA-E
Conjugate Unlabeled
Regulatory Status RUO

The monoclonal antibody 3D12 (HLA-E) recognizes human HLA-E, a member of the Human Leukocyte Antigen family. HLA-E is a MHC Class IB member, which has a specialized role in NK cell recognition. Binding of a restricted set of peptides derived from other Class I leader sequences to the HLA-E and B2M (beta2 microglobulin) complex leads to interaction with NKG2A on NK cells. This binding protects the HLA-G-expressing cell from NK cell killing. HLA-E expression is ubiquitous.