Histone Macro-H2A.1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA5121059

Product Code. 17772454

Description

Positive test controls include: A-549, HeLa, Rat brain. The target is usually found in the following locations: Chromosome, Nucleus. Immunogen sequence: KLEAIITPPP AKKAKSPSQK KPVSKKAGGK KGARKSKKKQ GEVSKAASAD STTEGTPADG FTVLSTKSLF LGQKLNLIHS EISNLAGFEV EAIINPTNAD IDLKDDLGNT LEKKGGKEFV EAVLELRKKN GPLEVAGAAV SAGHGLPAKF VIHCNSPVWG ADKCEELLEK TVKNCLALAD DKKLKSIAFP SIGSGRNGFP KQTAAQLILK AISSYFVSTM SSSIKTVYFV LFDSESIGIY VQEMAKLDAN

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Specifications

• Antigen: Histone Macro-H2A.1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MACROH2A1
• Gene Alias: Core histone macro-H2A.1; H2A histone family member Y; H2A histone family, member Y; H2A.y; H2A/y; H2AF12M; H2AFY; Histone H2A.y; histone macroH2A1; histone macroH2A1.1; histone macroH2A1.2; macroH2A1; MACROH2A1.1; macroH2A1.2; medulloblastoma antigen MU-MB-50.205; mH2A1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26914, 29384, 9555
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.65 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O75367, Q02874, Q9QZQ8
• Gene Symbols: MACROH2A1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 123-372 of human macroH2A1 (NP_6132582)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG