HGAL Mouse anti-Human, Clone: 1H1-A7, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9758-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15507646

Quantity Price
1 £ 61.7 / 25µg
Estimated Shipment date
from Supplier 08-05-2017
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Description and Specification

Specification

Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Antigen HGAL
Format Purified
Clone 1H1-A7
Applications Enzyme Linked Immunosorbent Assay
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Immunoprecipitation
Applications Microscopy
Applications Western Blotting
Concentration 0.5mg/mL
Quantity 25μg
Host Species Mouse
Primary or Secondary Primary
Gene Alias Human germinal center-associated lymphoma, GCET2
Isotype IgG2a
Storage Requirements Store at 2-8°C.
Species Reactivity Human, Mouse
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Conjugate Unlabeled

The monoclonal antibody 1H1-A7 recognizes human germinal center-associated lymphoma (HGAL) protein. HGAL is expressed in germinal centers, spleen, thymus, and germinal center-derived lymphomas. HGAL is localized to the cytoplasm of cells within the dark zone of the germinal center and functions to enhance the activation of RhoA leading to negative regulation of lymphocyte motility. HGAL expression has been used to help elucidate nodal marginal zone lymphoma (NMZL) from cases of diffuse follicle center lymphoma. Additionally, HGAL expression was shown to correlate with survival in patients with diffuse large B-cell lymphoma (DLBCL).

The 1H1-A7 antibody recognizes the protein product of the M17 gene, the mouse homolog of the HGAL protein.