missing translation for 'onlineSavingsMsg'
Learn More

Hesperadin hydrochloride, Tocris Bioscience™

Potent Aurora kinase B inhibitor

Brand:  RD Systems (Bio-Techne) 3988/50

Code : Z1

Additional Details : Weight : 0.00050kg

Quantity 50mg

 View more versions of this product

Product Code. 13433934

  • £854.07 / 50mg

Estimated Shipment date
from Supplier 26-03-2020

Please to purchase this item. Need a web account? Register with us today!


Description

Description

ATP-competitive inhibitor of Aurora B kinase (IC50 = 250 nM). Prevents chromosome alignment and segregation; also induces polyploidy and prevents histone H3-Ser10 phosphorylation. Overrides the spindle assembly checkpoint and induces mitotic exit in monastrol - and taxol -treated HeLa cells.
Specifications

Chemical Identifiers

422513-13-1
516.66
hesperadin, hesperadine, unii-ptr491os14, z-n-2-oxo-3-phenyl 4-piperidin-1-ylmethyl phenyl amino methylene indolin-5-yl ethanesulfonamide, n-3z-2-oxo-3-phenyl 4-piperidin-1-ylmethyl phenyl amino methylidene-2,3-dihydro-1h-indol-5-yl ethanesulfonamide, n-3z-2-oxo-3-phenyl 4-piperidin-1-ylmethyl phenyl amino methylidene-1h-indol-5-yl ethanesulfonamide, n-2,3-dihydro-2-oxo-3-3z-phenyl 4-1-piperidinylmethyl phenyl amino methylene-1h-indol-5-yl ethanesulfonamide, hesperadin/, d05wsm, ethanesulfonamide, n-2,3-dihydro-2-oxo-3-3z-phenyl 4-1-piperidinylmethyl phenyl amino methylene-1h-indol-5-yl
CHEBI:70726
CCS(=O)(=O)NC1=CC2=C(C=C1)NC(=O)C2=C(C3=CC=CC=C3)NC4=CC=C(C=C4)CN5CCCCC5
C29H32N4O3S
GLDSKRNGVVYJAB-DQSJHHFOSA-N
10142586
N-[(3Z)-2-oxo-3-[phenyl-[4-(piperidin-1-ylmethyl)anilino]methylidene]-1H-indol-5-yl]ethanesulfonamide

Specifications

50mg
422513-13-1
hesperadin, hesperadine, unii-ptr491os14, z-n-2-oxo-3-phenyl 4-piperidin-1-ylmethyl phenyl amino methylene indolin-5-yl ethanesulfonamide, n-3z-2-oxo-3-phenyl 4-piperidin-1-ylmethyl phenyl amino methylidene-2,3-dihydro-1h-indol-5-yl ethanesulfonamide, n-3z-2-oxo-3-phenyl 4-piperidin-1-ylmethyl phenyl amino methylidene-1h-indol-5-yl ethanesulfonamide, n-2,3-dihydro-2-oxo-3-3z-phenyl 4-1-piperidinylmethyl phenyl amino methylene-1h-indol-5-yl ethanesulfonamide, hesperadin/, d05wsm, ethanesulfonamide, n-2,3-dihydro-2-oxo-3-3z-phenyl 4-1-piperidinylmethyl phenyl amino methylene-1h-indol-5-yl
CCS(=O)(=O)NC1=CC2=C(C=C1)NC(=O)C2=C(C3=CC=CC=C3)NC4=CC=C(C=C4)CN5CCCCC5
516.66
CHEBI:70726
>99%
Hesperadin hydrochloride
C29H32N4O3S
GLDSKRNGVVYJAB-DQSJHHFOSA-N
N-[(3Z)-2-oxo-3-[phenyl-[4-(piperidin-1-ylmethyl)anilino]methylidene]-1H-indol-5-yl]ethanesulfonamide
10142586
553.12
Videos
Documents