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Helios Armenian Hamster, PE-eFluor 610, Clone: 22F6, eBioscience™

Armenian Hamster Monoclonal Antibody

Brand:  Affymetrix eBioscience 61-9883-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15500587

  • £105.08 / 25 tests


EU Stock 2
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Disclaimers:

For Research Use Only.


Description

Description

This 22F6 monoclonal antibody reacts with human, mouse and canine Helios. Helios is a zinc-finger transcription factor first identified for its similarity to Ikaros. It is expressed in hematopoietic stem cells in both the embryo and adult mice. While the highest expression is found in regulatory T cells, Helios is not expressed in mature B cells, dendritic cells or myeloid cells. Helios can form a homodimer as well as heterodimerize with other Ikaros family members to regulate transcription. Eight isoforms of Helios exist, some of which possess a dominant-negative function that has also been found to be upregulated in lymphoid malignancies, including T-acute lymphoblastic leukemia.

22F6 has been reported to cross react with rat Helios.
Specifications

Specifications

Helios
22F6
PE-eFluor 610
Conjugated
Armenian Hamster
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Monoclonal
Flow Cytometry (Intracellular Staining)
5μL (0.03μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Ikaros family zinc finger 2
IgG
RUO
Primary
Murine