Helios Armenian Hamster, eFluor 450, Clone: 22F6, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 48-9883-41

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 2.00000kg



Disclaimers: For Research Use Only.

Product Code. 15232018

Quantity Price
1 £ 90.41 / Each
EU Stock 3
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Description and Specification

Specification

Host Species Armenian Hamster
Clone 22F6
Isotype IgG
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 25 tests
Concentration 5μL (0.03μg)/test
Applications Flow Cytometry (Intracellular Staining)
Conjugate eFluor 450
Gene Alias Ikaros family zinc finger 2
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Format Conjugated
Antigen Helios
Regulatory Status RUO
Species Reactivity Canine, Human, Mouse

This 22F6 monoclonal antibody reacts with human, mouse and canine Helios. Helios is a zinc-finger transcription factor first identified for its similarity to Ikaros. It is expressed in hematopoietic stem cells in both the embryo and adult mice. While the highest expression is found in regulatory T cells, Helios is not expressed in mature B cells, dendritic cells or myeloid cells. Helios can form a homodimer as well as heterodimerize with other Ikaros family members to regulate transcription. Eight isoforms of Helios exist, some of which possess a dominant-negative function that has also been found to be upregulated in lymphoid malignancies, including T-acute lymphoblastic leukemia.

22F6 has been reported to cross react with rat Helios.