Helios Armenian Hamster, eFluor 450, Clone: 22F6, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 48-9883-42

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.10000kg



Disclaimers: For Research Use Only.

Product Code. 15230969

Quantity Price
1 £ 223.57999999999998 / 100 tests
EU Stock 49
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Description and Specification

Specification

Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Flow Cytometry (Intracellular Staining)
Quantity 100 tests
Primary or Secondary Primary
Conjugate eFluor 450
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone 22F6
Antigen Helios
Regulatory Status RUO
Format Conjugated
Isotype IgG
Monoclonal or Polyclonal Monoclonal
Species Reactivity Canine, Human, Mouse
Concentration 5μL (0.03μg)/test
Gene Alias Ikaros family zinc finger 2
Host Species Armenian Hamster

This 22F6 monoclonal antibody reacts with human, mouse and canine Helios. Helios is a zinc-finger transcription factor first identified for its similarity to Ikaros. It is expressed in hematopoietic stem cells in both the embryo and adult mice. While the highest expression is found in regulatory T cells, Helios is not expressed in mature B cells, dendritic cells or myeloid cells. Helios can form a homodimer as well as heterodimerize with other Ikaros family members to regulate transcription. Eight isoforms of Helios exist, some of which possess a dominant-negative function that has also been found to be upregulated in lymphoid malignancies, including T-acute lymphoblastic leukemia.

22F6 has been reported to cross react with rat Helios.