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HDS 029, Tocris Bioscience™

Potent inhibitor of the ErbB receptor family

Brand:  Tocris (Bio-Techne) 264610

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13441644

  • £227.85 / 10mg

Estimated Shipment date
from Supplier 26-11-2019

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Description

Description

Potent inhibitor of the ErbB receptor family (IC50 values are 0.3, 0.5 and 1.1 nM for ErbB1 (EGFR), ErbB4 and ErbB2 respectively). Inhibits EGF-induced erbB1 autophosphorylation in NIH3T3 cells and heregulin-stimulated ErbB autophosphorylation in MDA-MB-453 human breast carcinoma cells (IC50 values are 2.5 and 24 nM respectively).
Specifications

Chemical Identifiers

881001-19-0
355.757
egfr/erbb-2/erbb-4 inhibitor, unii-zn0x0q76f1, n-4-3-chloro-4-fluorophenyl amino pyrido 3,4-d pyrimidin-6-yl 2-butynamide, n-4-3-chloro-4-fluorophenyl amino pyrido 3,4-d pyrimidin-6-yl but-2-ynamide, n-4-3-chloro-4-fluorophenyl amino pyrido 3,4-d pyrimidin-6-yl-2-butynamide, d05fft, tki-39
N-[4-(3-chloro-4-fluoroanilino)pyrido[3,4-d]pyrimidin-6-yl]but-2-ynamide
C17H11ClFN5O
DLPSDPPZXRJQOY-UHFFFAOYSA-N
11566580
CC#CC(=O)NC1=NC=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl

Specifications

10mg
881001-19-0
egfr/erbb-2/erbb-4 inhibitor, unii-zn0x0q76f1, n-4-3-chloro-4-fluorophenyl amino pyrido 3,4-d pyrimidin-6-yl 2-butynamide, n-4-3-chloro-4-fluorophenyl amino pyrido 3,4-d pyrimidin-6-yl but-2-ynamide, n-4-3-chloro-4-fluorophenyl amino pyrido 3,4-d pyrimidin-6-yl-2-butynamide, d05fft, tki-39
CC#CC(=O)NC1=NC=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl
355.757
355.76
HDS 029
C17H11ClFN5O
DLPSDPPZXRJQOY-UHFFFAOYSA-N
N-[4-(3-chloro-4-fluoroanilino)pyrido[3,4-d]pyrimidin-6-yl]but-2-ynamide
11566580
>97%
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