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GW 843682X, Tocris Bioscience™
Selective inhibitor of PLK1 and PLK3
Brand: RD Systems (Bio-Techne) 29771
Code : Z1
Additional Details : Weight : 0.01000kg
Quantity | 1mg |
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Description
Selective inhibitor of polo-like kinase 1 (PLK1) and polo-like kinase 3 (PLK3) (IC50 values are 2.2 and 9.1 nM respectively). Displays > 100-fold selectivity over ∽30 other kinases tested including cdk1 and cdk2. Inhibits proliferation of most tumor cells in vitro and is selective over normal diploid fibroblasts.Chemical Identifiers
660868-91-7 | |
477.458 | |
5-5,6-dimethoxy-1h-benzimidazol-1-yl-3-2-trifluoromethyl-benzyl oxy thiophene-2-carboxamide, 5-5,6-dimethoxy-1h-benzimidazol-1-yl-3-2-trifluoromethyl benzyl oxy thiophene-2-carboxamide, 5-5,6-dimethoxybenzimidazol-1-yl-3-2-trifluoromethyl phenyl methoxy thiophene-2-carboxamide, kinome_3462, thiophene deriv., 20, bmcl191018 compound 2, gw843682x hplc , solid, 3-2-trifluoromethyl benzyloxy-5-5,6-dimethoxy-1h-benzo d imidazol-1-yl thiophene-2-carboxamide, 5-5,6-dimethoxy-1,3-benzodiazol-1-yl-3-2-trifluoromethyl phenyl methoxy thiophene-2-carboxamide, 5-5,6-dimethoxy-1-benzimidazolyl-3-2-trifluoromethyl phenyl methoxy-2-thiophenecarboxamide | |
5-(5,6-dimethoxybenzimidazol-1-yl)-3-[[2-(trifluoromethyl)phenyl]methoxy]thiophene-2-carboxamide |
C22H18F3N3O4S | |
JSKUWFIZUALZLX-UHFFFAOYSA-N | |
9826308 | |
COC1=C(C=C2C(=C1)N=CN2C3=CC(=C(S3)C(=O)N)OCC4=CC=CC=C4C(F)(F)F)OC |
Specifications
GW 843682X | |
660868-91-7 | |
5-5,6-dimethoxy-1h-benzimidazol-1-yl-3-2-trifluoromethyl-benzyl oxy thiophene-2-carboxamide, 5-5,6-dimethoxy-1h-benzimidazol-1-yl-3-2-trifluoromethyl benzyl oxy thiophene-2-carboxamide, 5-5,6-dimethoxybenzimidazol-1-yl-3-2-trifluoromethyl phenyl methoxy thiophene-2-carboxamide, kinome_3462, thiophene deriv., 20, bmcl191018 compound 2, gw843682x hplc , solid, 3-2-trifluoromethyl benzyloxy-5-5,6-dimethoxy-1h-benzo d imidazol-1-yl thiophene-2-carboxamide, 5-5,6-dimethoxy-1,3-benzodiazol-1-yl-3-2-trifluoromethyl phenyl methoxy thiophene-2-carboxamide, 5-5,6-dimethoxy-1-benzimidazolyl-3-2-trifluoromethyl phenyl methoxy-2-thiophenecarboxamide | |
COC1=C(C=C2C(=C1)N=CN2C3=CC(=C(S3)C(=O)N)OCC4=CC=CC=C4C(F)(F)F)OC | |
477.458 | |
477.46 |
1mg | |
C22H18F3N3O4S | |
JSKUWFIZUALZLX-UHFFFAOYSA-N | |
5-(5,6-dimethoxybenzimidazol-1-yl)-3-[[2-(trifluoromethyl)phenyl]methoxy]thiophene-2-carboxamide | |
9826308 | |
>98% |