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GW 843682X, Tocris Bioscience™

Selective inhibitor of PLK1 and PLK3

Brand:  RD Systems (Bio-Techne) 29771

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 1mg

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Product Code. 13462174

  • £93.15 / 1mg


Estimated Shipment
03-09-2018
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Description

Description

Selective inhibitor of polo-like kinase 1 (PLK1) and polo-like kinase 3 (PLK3) (IC50 values are 2.2 and 9.1 nM respectively). Displays > 100-fold selectivity over ∽30 other kinases tested including cdk1 and cdk2. Inhibits proliferation of most tumor cells in vitro and is selective over normal diploid fibroblasts.
Specifications

Chemical Identifiers

660868-91-7
477.458
5-(5, 6-Dimethoxy-1H-benzimidazol-1-yl)-3-[[2-(trifluoromethyl)phenyl]methoxy]-2-thiophenecarboxamide
C22H18F3N3O4S
JSKUWFIZUALZLX-UHFFFAOYSA-N
9826308

Specifications

GW 843682X
>98%
1mg
JSKUWFIZUALZLX-UHFFFAOYSA-N
5-(5,6-dimethoxybenzimidazol-1-yl)-3-[[2-(trifluoromethyl)phenyl]methoxy]thiophene-2-carboxamide
9826308
660868-91-7
C22H18F3N3O4S
5-(5, 6-Dimethoxy-1H-benzimidazol-1-yl)-3-[[2-(trifluoromethyl)phenyl]methoxy]-2-thiophenecarboxamide
COC1=C(C=C2C(=C1)N=CN2C3=CC(=C(S3)C(=O)N)OCC4=CC=CC=C4C(F)(F)F)OC
477.458
477.46
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