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GW 788388, Tocris Bioscience™

Potent and selective inhibitor of TGF-βRI

Brand:  RD Systems (Bio-Techne) 3264/50

Code : Z1

Additional Details : Weight : 0.00050kg

Quantity 50mg

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Product Code. 13432684

  • £958.44 / 50mg

Estimated Shipment date
from Supplier 24-03-2020

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Description

Description

Potent inhibitor of transforming growth factor-β type I receptor (ALK5) (IC50 values are 18 and 93 nM for ALK5 binding and for TGF-β cellular assay respectively). Inhibits esophageal squamous cell carcinoma (ESCC)-induced neoangiogenesis. Orally active.
Specifications

Chemical Identifiers

452342-67-5
425.492
4-4-3-pyridin-2-yl-1h-pyrazol-4-yl pyridin-2-yl-n-tetrahydro-2h-pyran-4-yl benzamide, n-oxan-4-yl-4-4-3-pyridin-2-yl-1h-pyrazol-4-yl pyridin-2-yl benzamide, 4-4-3-pyridin-2-yl-1h-pyrazol-4-yl pyridin-2-yl-n-tetrahydropyran-4-yl benzamide, d0c3ad, benzamide, 4-4-3-2-pyridinyl-1h-pyrazol-4-yl-2-pyridinyl-n-tetrahydro-2h-pyran-4-yl, 4-4-3-pyridin-2-yl-1h-pyrazol-4-yl pyridin-2-y, n-oxan-4-yl-4-4-5-pyridin-2-yl-1h-pyrazol-4-yl pyridin-2-yl benzamide, n-oxan-4-yl-4-4-3-pyridin-2-yl-2h-pyrazol-4-yl pyridin-2-yl benzamide, 4-4-5-pyridin-2-yl-1h-pyrazol-4-yl pyridin-2-yl-n-tetrahydro-2h-pyran-4-yl benzamide
N-(oxan-4-yl)-4-[4-(5-pyridin-2-yl-1H-pyrazol-4-yl)pyridin-2-yl]benzamide
C25H23N5O2
SAGZIBJAQGBRQA-UHFFFAOYSA-N
10202642
C1COCCC1NC(=O)C2=CC=C(C=C2)C3=NC=CC(=C3)C4=C(NN=C4)C5=CC=CC=N5

Specifications

50mg
452342-67-5
4-4-3-pyridin-2-yl-1h-pyrazol-4-yl pyridin-2-yl-n-tetrahydro-2h-pyran-4-yl benzamide, n-oxan-4-yl-4-4-3-pyridin-2-yl-1h-pyrazol-4-yl pyridin-2-yl benzamide, 4-4-3-pyridin-2-yl-1h-pyrazol-4-yl pyridin-2-yl-n-tetrahydropyran-4-yl benzamide, d0c3ad, benzamide, 4-4-3-2-pyridinyl-1h-pyrazol-4-yl-2-pyridinyl-n-tetrahydro-2h-pyran-4-yl, 4-4-3-pyridin-2-yl-1h-pyrazol-4-yl pyridin-2-y, n-oxan-4-yl-4-4-5-pyridin-2-yl-1h-pyrazol-4-yl pyridin-2-yl benzamide, n-oxan-4-yl-4-4-3-pyridin-2-yl-2h-pyrazol-4-yl pyridin-2-yl benzamide, 4-4-5-pyridin-2-yl-1h-pyrazol-4-yl pyridin-2-yl-n-tetrahydro-2h-pyran-4-yl benzamide
C1COCCC1NC(=O)C2=CC=C(C=C2)C3=NC=CC(=C3)C4=C(NN=C4)C5=CC=CC=N5
425.492
425.48
GW 788388
C25H23N5O2
SAGZIBJAQGBRQA-UHFFFAOYSA-N
N-(oxan-4-yl)-4-[4-(5-pyridin-2-yl-1H-pyrazol-4-yl)pyridin-2-yl]benzamide
10202642
>98%
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