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GW 4064, Tocris Bioscience™

Selective farnesoid X receptor (FXR) agonist

Brand:  Tocris (Bio-Techne) 247310

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13461284

  • £133.65 / 10mg


Estimated Shipment
29-11-2018
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Description

Description

Selective, non-steroidal farnesoid X receptor (FXR) agonist (EC50 = 15 nM). Displays no activity at other nuclear receptors at concentrations up to 1 μM. Improves hyperglycaemia and hyperlipidemia in diabetic db/db mice. Shown to suppress autophagy in nutrient-deprived mouse hepatocytes.
Specifications

Chemical Identifiers

278779-30-9
542.837
e-3-2-chloro-4-3-2,6-dichlorophenyl-5-isopropylisoxazol-4-yl methoxy styryl benzoic acid, unii-sr225wuz0h, sr225wuz0h, 3-2-2-chloro-4-3-2,6-dichlorophenyl-5-isopropylisoxazol-4-ylmethoxy phenyl vinyl benzoic acid, benzoic acid, 3-2-2-chloro-4-3-2,6-dichlorophenyl-5-1-methylethyl-4-isoxazolyl methoxy phenyl ethenyl, 3-2,6-dichlorophenyl-4-3'-carboxy-2-chlorostilben-4-yl oxymethyl-5-isopropylisoxazole, 3-e-2-2-chloro-4-3-2,6-dichlorophenyl-5-1-methylethyl isoxazol-4-yl methoxy phenyl ethenyl benzoic acid, 3-e-2-2-chloro-4-3-2,6-dichlorophenyl-5-propan-2-yl-1,2-oxazol-4-yl methoxy phenyl ethenyl benzoic acid, 3-e-2-2-chloro-4-3-2,6-dichlorophenyl-5-propan-2-yl-1,2-oxazol-4-yl methoxy phenyl ethenyl benzoic acid, 3-2-2-chloro-4-3-2,6-dichlorophenyl-5-1-methylethyl-4-isoxazolyl methoxy phenyl ethenyl benzoic acid
CHEBI:79997
CC(C)C1=C(C(=NO1)C2=C(C=CC=C2Cl)Cl)COC3=CC(=C(C=C3)C=CC4=CC(=CC=C4)C(=O)O)Cl
C28H22Cl3NO4
BYTNEISLBIENSA-MDZDMXLPSA-N
9893571
3-[(E)-2-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]ethenyl]benzoic acid

Specifications

GW 4064
278779-30-9
e-3-2-chloro-4-3-2,6-dichlorophenyl-5-isopropylisoxazol-4-yl methoxy styryl benzoic acid, unii-sr225wuz0h, sr225wuz0h, 3-2-2-chloro-4-3-2,6-dichlorophenyl-5-isopropylisoxazol-4-ylmethoxy phenyl vinyl benzoic acid, benzoic acid, 3-2-2-chloro-4-3-2,6-dichlorophenyl-5-1-methylethyl-4-isoxazolyl methoxy phenyl ethenyl, 3-2,6-dichlorophenyl-4-3'-carboxy-2-chlorostilben-4-yl oxymethyl-5-isopropylisoxazole, 3-e-2-2-chloro-4-3-2,6-dichlorophenyl-5-1-methylethyl isoxazol-4-yl methoxy phenyl ethenyl benzoic acid, 3-e-2-2-chloro-4-3-2,6-dichlorophenyl-5-propan-2-yl-1,2-oxazol-4-yl methoxy phenyl ethenyl benzoic acid, 3-e-2-2-chloro-4-3-2,6-dichlorophenyl-5-propan-2-yl-1,2-oxazol-4-yl methoxy phenyl ethenyl benzoic acid, 3-2-2-chloro-4-3-2,6-dichlorophenyl-5-1-methylethyl-4-isoxazolyl methoxy phenyl ethenyl benzoic acid
CC(C)C1=C(C(=NO1)C2=C(C=CC=C2Cl)Cl)COC3=CC(=C(C=C3)C=CC4=CC(=CC=C4)C(=O)O)Cl
542.837
CHEBI:79997
>97%
10mg
C28H22Cl3NO4
BYTNEISLBIENSA-MDZDMXLPSA-N
3-[(E)-2-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]ethenyl]benzoic acid
9893571
542.84
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