missing translation for 'onlineSavingsMsg'
Learn More

Guggulsterone, Tocris Bioscience™

Broad spectrum steroid receptor ligand. Antagonizes FXR and displays hypolipidemic activity

Brand:  Tocris (Bio-Techne) 201310

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

 View more versions of this product

Product Code. 13460404

  • £151.80 / 10mg


Estimated Shipment
03-12-2018
Add to basket

Description

Description

Broad spectrum steroid receptor ligand; binds with high affinity to mineralocorticoid receptors (Ki = 39 nM) and lower affinity to progesterone, androgen and glucocorticoid receptors (Ki values are 201, 240 and 224 nM respectively). Functions primarily as an antagonist of these receptors, with the exception of the progesterone receptor where it displays partial agonist effects. Also exerts hypolipidemic activity, likely via antagonism of the receptor for bile acids (farnesoid X receptor; FXR).
Specifications

Chemical Identifiers

95975-55-6
312.453
guggulsterone
(8S,9R,10R,13R,14S,17E)-17-ethylidene-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthrene-3,16-dione
C21H28O2
WDXRGPWQVHZTQJ-PXYKUDORSA-N
122173093
CC=C1C(=O)CC2C1(CCC3C2CCC4=CC(=O)CCC34C)C

Specifications

Guggulsterone
95975-55-6
guggulsterone
CC=C1C(=O)CC2C1(CCC3C2CCC4=CC(=O)CCC34C)C
312.453
312.45
10mg
C21H28O2
WDXRGPWQVHZTQJ-PXYKUDORSA-N
(8S,9R,10R,13R,14S,17E)-17-ethylidene-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthrene-3,16-dione
122173093
>99%
Videos