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Guggulsterone, Tocris Bioscience™

Broad spectrum steroid receptor ligand. Antagonizes FXR and displays hypolipidemic activity

Brand:  Tocris (Bio-Techne) 201310

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13460404

  • £151.80 / 10mg


Estimated Shipment
04-10-2018
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Description

Description

Broad spectrum steroid receptor ligand; binds with high affinity to mineralocorticoid receptors (Ki = 39 nM) and lower affinity to progesterone, androgen and glucocorticoid receptors (Ki values are 201, 240 and 224 nM respectively). Functions primarily as an antagonist of these receptors, with the exception of the progesterone receptor where it displays partial agonist effects. Also exerts hypolipidemic activity, likely via antagonism of the receptor for bile acids (farnesoid X receptor; FXR).
Specifications

Chemical Identifiers

95975-55-6
312.453
Pregna-4, 17(20)-diene-3, 16-dione
C21H28O2
WDXRGPWQVHZTQJ-PXYKUDORSA-N
122173093

Specifications

Guggulsterone
>99%
Pregna-4, 17(20)-diene-3, 16-dione
CC=C1C(=O)CC2C1(CCC3C2CCC4=CC(=O)CCC34C)C
312.453
312.45
95975-55-6
C21H28O2
WDXRGPWQVHZTQJ-PXYKUDORSA-N
(8S,9R,10R,13R,14S,17E)-17-ethylidene-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthrene-3,16-dione
122173093
10mg
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