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Guggulsterone, Tocris Bioscience™

Broad spectrum steroid receptor ligand. Antagonizes FXR and displays hypolipidemic activity

Brand:  Tocris (Bio-Techne) 201310

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13460404

  • £155.00 / 10mg


Estimated Shipment
29-06-2018
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Description

Description

Broad spectrum steroid receptor ligand; binds with high affinity to mineralocorticoid receptors (Ki = 39 nM) and lower affinity to progesterone, androgen and glucocorticoid receptors (Ki values are 201, 240 and 224 nM respectively). Functions primarily as an antagonist of these receptors, with the exception of the progesterone receptor where it displays partial agonist effects. Also exerts hypolipidemic activity, likely via antagonism of the receptor for bile acids (farnesoid X receptor; FXR).
Specifications

Chemical Identifiers

Guggulsterone
C21H28O2
312.45
Pregna-4, 17(20)-diene-3, 16-dione

Specifications

Guggulsterone
>99%
312.45
10mg
95975-55-6
C21H28O2
Pregna-4, 17(20)-diene-3, 16-dione
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