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Guanidine hydrochloride, 98%, Thermo Scientific Chemicals
Description
Guanidine hydrochloride is used for purification of proteins and nucleic acids. It can be used as a medicine, organic synthesis intermediate and is used in dyes. It acts as an intermediate in the preparation of sulfadiazine, which is an important raw material for sulfamethyldiazine, sulfamethazine and folic acid. It is utilized in the synthesis of 2-amino-pyrimidine, 2- amino -6- methyl-pyrimidine and 2-amino -4,6 - dimethyl-pyrimidine. Also used in RNA isolation to dissociate nucleoproteins and inhibit RNase.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Guanidine hydrochloride is the hydrochloride salt of guanidine, an acetylcholine releasing agent
- It is a normal product of protein metabolism and is sometimes used for pyrimidine synthesis
Application
- Guanidine hydrochloride is a powerful denaturant, useful for taking nucleic acids (DNA and RNA) and proteins out of their native conformation
- Guanidine hydrochloride acts as a strong organic base at physiological pH
- It is suitable for use in protein and nucleic acid purification protocols
Specifications
| Melting Point | 178°C to 185°C |
| Density | 1.344 |
| Quantity | 250 g |
| Beilstein | 3591990 |
| Sensitivity | Hygroscopic |
| Merck Index | 144562 |
| Solubility Information | Soluble in water and ethanol. |
| Formula Weight | 95.53 |
| Percent Purity | 98% |
| Chemical Name or Material | Guanidine hydrochloride |
RUO – Research Use Only