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GSK J4, Tocris Bioscience™

Histone KDM inhibitor; cell permeable

Brand:  RD Systems (Bio-Techne) 4594/10

Code : Z1

Additional Details : Weight : 0.00010kg

Quantity 10mg

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Product Code. 13464964

  • £180.00 / 10mg


Estimated Shipment
05-07-2018
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Description

Description

Histone lysine demethylase (KDM) inhibitor; blocks demethylation of histone H3K27. Attenuates lipopolysaccharide (LPS)-induced proinflammatory cytokine production in primary human macrophages (IC50 = 9μM for the inhibition of TNFα release). Cell permeable. Ethyl ester derivative of GSK J1 (Cat. No. 4593).
Specifications

Chemical Identifiers

GSK J4
C24H27N5O2
417.5
N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester

Specifications

GSK J4
>99%
417.5
10mg
1373423-53-0
C24H27N5O2
N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester
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