Granzyme M Mouse anti-Human, eFluor 660, Clone: 4B2G4, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-9774-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15500137

Quantity Price
1 £ 91.11 / 25 tests
EU Stock 4
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Description and Specification

Specification

Isotype IgG1
Host Species Mouse
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone 4B2G4
Regulatory Status RUO
Concentration 5μL (0.125μg)/test
Quantity 25 tests
Primary or Secondary Primary
Applications Flow Cytometry (Intracellular Staining)
Format Conjugated
Monoclonal or Polyclonal Monoclonal
Conjugate eFluor 660
Species Reactivity Human
Antigen Granzyme M
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

Granzyme M is one of five granzyme serine proteases that have been indentified in humans. These proteins are expressed in the granules of NK cells and cytotoxic T cells, and are critical for the induction of target cell apoptosis through the cleavage of intracellular substrates. Although not as well characterized as some of the other family members, Granzyme M has been found to exhibit some distinct functions. These include the non-cytotoxic inhibition of cytomegalovirus replication, induction of apoptosis in tumor cells, and contribution to the TLR4-induced inflammatory process.