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Granzyme M Monoclonal Antibody (4B2G4), eFluor™ 660, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 50-9774-42
Code : NEW
Additional Details : Weight : 0.23750kg
Description
Description: Granzyme M is one of five granzyme serine proteases that have been identified in humans. These proteins are expressed in the granules of NK cells and cytotoxic T cells, and are critical for the induction of target cell apoptosis through the cleavage of intracellular substrates. Although not as well characterized as some of the other family members, Granzyme M has been found to exhibit some distinct functions. These include the non-cytotoxic inhibition of cytomegalovirus replication, induction of apoptosis in tumor cells, and contribution to the TLR4-induced inflammatory process. Applications Reported: This 4B2G4 antibody has been reported for use in intracellular staining followed by flow cytometric analysis. Applications Tested: This 4B2G4 antibody has been pre-titrated and tested by intracellular staining followed by flow cytometric analysis of normal human peripheral blood cells using the Intracellular Fixation & Permeabilization Buffer Set (cat. 88-8824) and protocol. Please refer to Best Protocols: Protocol A: Two step protocol for (cytoplasmic) intracellular proteins located under the Resources Tab online. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.
Granzyme M Monoclonal antibody specifically detects Granzyme M in Human samples. It is validated for Flow Cytometry.Specifications
Granzyme M | |
Monoclonal | |
5 μL/Test | |
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2 | |
P51124 | |
GZMM | |
Affinity chromatography | |
RUO | |
3004 | |
4° C, store in dark, DO NOT FREEZE! | |
Liquid |
Flow Cytometry | |
4B2G4 | |
eFluor 660 | |
GZMM | |
granzyme M; granzyme M (lymphocyte met-ase 1); GZMM; Hu-Met-1; Lmet1; lymphoctye Met-ase 1; lymphocyte met-ase 1; MET1; Met-1 serine protease; Met-ase; MMET-1; natural killer cell granular protease; RNK-Met-1 | |
Mouse | |
100 Tests | |
Primary | |
Human | |
Antibody | |
IgG1 κ |
For Research Use Only.