Granzyme K Mouse anti-Human, PerCP-eFluor 710, Clone: G3H69, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-8897-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15509386

Quantity Price
1 £ 75.3 / 25 tests
Estimated Shipment date
from Supplier 10-05-2017
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Description and Specification

Specification

Primary or Secondary Primary
Format Conjugated
Applications Flow Cytometry (Intracellular Staining)
Conjugate PerCP-eFluor 710
Concentration 5μL (0.03μg)/test
Species Reactivity Human
Regulatory Status RUO
Antigen Granzyme K
Clone G3H69
Host Species Mouse
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Isotype IgG2a
Gene Alias GZMK, Granzyme 3, TRYP2
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Quantity 25 tests
Monoclonal or Polyclonal Monoclonal

This G3H69 monoclonal antibody reacts with human Granzyme K. Granzyme K is one of five granzyme serine proteases that have been identified in humans. These proteins are expressed in the granules of NK cells and cytotoxic T cells, and are critical for the induction of target cell apoptosis through the cleavage of intracellular substrates. Granzyme A and Granzyme K are both tryptases and appear to show overlapping, though not identical, substrate specificity. This functional similarity is believed to account for the minimal decrease in cytotoxicity of Granzyme A-deficient CTLs.