Granzyme K Mouse anti-Human, eFluor 660, Clone: G3H69, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-8897-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15540057

Quantity Price
1 £ 66.65 / 25 tests
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Format Conjugated
Primary or Secondary Primary
Concentration 5μL (0.03μg)/test
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias GZMK, Granzyme 3, TRYP2
Conjugate eFluor 660
Antigen Granzyme K
Quantity 25 tests
Species Reactivity Human
Applications Flow Cytometry (Intracellular Staining)
Monoclonal or Polyclonal Monoclonal
Isotype IgG2a
Host Species Mouse
Clone G3H69
Regulatory Status RUO

This G3H69 monoclonal antibody reacts with human Granzyme K. Granzyme K is one of five granzyme serine proteases that have been indentified in humans. These proteins are expressed in the granules of NK cells and cytotoxic T cells, and are critical for the induction of target cell apoptosis through the cleavage of intracellular substrates. Granzyme A and Granzyme K are both tryptases and appear to show overlapping, though not identical, substrate specificity. This functional similarity is believed to account for the minimal decrease in cytotoxicity of Granzyme A-deficient CTLs.