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Granzyme K, eFluor 660, clone: G3H69, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 50-8897-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15550057

  • £174.50 / 100 tests


Estimated Shipment date
from Supplier 01-06-2018
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Description

Description

Description: This G3H69 monoclonal antibody reacts with human Granzyme K. Granzyme K is one of five granzyme serine proteases that have been indentified in humans. These proteins are expressed in the granules of NK cells and cytotoxic T cells, and are critical for the induction of target cell apoptosis through the cleavage of intracellular substrates. Granzyme A and Granzyme K are both tryptases and appear to show overlapping, though not identical, substrate specificity. This functional similarity is believed to account for the minimal decrease in cytotoxicity of Granzyme A-deficient CTLs.Applications Reported: This G3H69 antibody has been reported for use in intracellular staining followed by flow cytometric analysis.Applications Tested: This G3H69 antibody has been pre-titrated and tested by intracellular staining followed by flow cytometric analysis. This can be used at 5 μL (0.03 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. eFluor® 660 is a replacement for Alexa Fluor® 647. eFluor® 660 emits at 659 nm and is excited with the red laser (633 nm). Please make sure that your instrument is capable of detecting this fluorochome.Excitation: 633-647 nm; Emission: 668 nm; Laser: Red Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

Granzyme K
Monoclonal
5μl/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P49863
GrK
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
G3H69
eFluor 660
GZMK
Conjugated
GZMK
IgG2a, kappa
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
3003
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