Granzyme K Mouse anti-Human, eFluor 660, Clone: G3H69, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-8897-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15550057

Quantity Price
1 £ 170.59 / 100 tests
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Applications Flow Cytometry (Intracellular Staining)
Isotype IgG2a
Clone G3H69
Primary or Secondary Primary
Host Species Mouse
Species Reactivity Human
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Regulatory Status RUO
Concentration 5μL (0.03μg)/test
Quantity 100 tests
Antigen Granzyme K
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Conjugate eFluor 660
Gene Alias GZMK, Granzyme 3, TRYP2
Format Conjugated
Monoclonal or Polyclonal Monoclonal

This G3H69 monoclonal antibody reacts with human Granzyme K. Granzyme K is one of five granzyme serine proteases that have been indentified in humans. These proteins are expressed in the granules of NK cells and cytotoxic T cells, and are critical for the induction of target cell apoptosis through the cleavage of intracellular substrates. Granzyme A and Granzyme K are both tryptases and appear to show overlapping, though not identical, substrate specificity. This functional similarity is believed to account for the minimal decrease in cytotoxicity of Granzyme A-deficient CTLs.