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Granzyme A Monoclonal Antibody (CB9), PE-Cyanine7, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

£124.00 - £294.00

Specifications

Antigen Granzyme A
Clone CB9
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
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Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15508656
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Affymetrix eBioscience
25-9177-41
25 Tests
£124.00
25 tests
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Estimated Shipment: 25-04-2024
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15518656
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Affymetrix eBioscience
25-9177-42
100 Tests
£294.00
100 tests
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Estimated Shipment: 27-03-2024
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Description

Description

Description: This CB9 monoclonal antibody reacts with human Granzyme A. Granzyme A is the most abundantly expressed of the granzyme serine proteases, which are proteins released from the granules of NK cells and cytotoxic T lymphocytes that induce death in target cells by cleavage of intracellular substrates. They play a critical role in immune defense against viruses, tumors, and intracellular bacteria. Granzyme A activates caspase-independent cell death pathways morphologically similar to apoptosis and characterized by mitochondrial and DNA damage. It may also play a role in inflammation, as the precursor form of IL-1 beta (pro-IL-1 beta) is among its target substrates. Granzyme A shares overlapping substrate specificity with the closely-related Granzyme K, which is believed to account for the minimal decrease in cytotoxicity of Granzyme A-deficient CTL. Applications Reported: This CB9 antibody has been reported for use in intracellular staining followed by flow cytometric analysis. Applications Tested: This CB9 antibody has been pre-titrated and tested by intracellular staining followed by flow cytometric analysis of stimulated normal human peripheral blood cells using the Intracellular Fixation & Permeabilization Buffer Set (cat. 88-8824) and protocol. Please refer to Best Protocols: Protocol A: Two step protocol for (cytoplasmic) intracellular proteins located under the Resources Tab online. This can be used at 5 μL (0.25 μg) per test.

Granzyme A Monoclonal antibody specifically detects Granzyme A in Human samples. It is validated for Flow Cytometry.
Specifications

Specifications

Granzyme A
5 μL/Test
Monoclonal
Liquid
RUO
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Autocrine thymic lymphoma granzyme-like serine protease; AW494114; BLT esterase; CTL tryptase; CTLA3; CTLA-3; Cytotoxic T-lymphocyte proteinase 1; Cytotoxic T-lymphocyte-associated serine esterase-3; fragmentin-1; granzyme 1; granzyme A; Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3; Hanukah factor serine protease); granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3); Granzyme-1; GZMA; H factor; Hanukah factor; Hanukah factor serine protease); Hanukkah factor; Hf; HFSP; Mtsp-1; SE1; serine esterase 1; t cell-specific serine protease 1; TSP1; TSP-1
GZMA
Primary
4° C, store in dark, DO NOT FREEZE!
GZMA
CB9
Flow Cytometry
PE-Cyanine7
Mouse
Human
P12544
3001
IgG1 κ
Affinity chromatography
Antibody
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