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GR 159897, Tocris Bioscience™

Non-peptide, potent NK2 antagonist

Brand:  Tocris (Bio-Techne) 127410

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

 View more versions of this product

Product Code. 13469033

  • £219.03 / 10mg

Estimated Shipment date
from Supplier 25-03-2020

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Description

Description

A potent, selective, non-peptide, orally active neurokinin NK2 receptor antagonist. Competes for binding of [3H]GR100679 to hNK2-transfected CHO cells with a pKi of 9.5. Inhibits NK2 receptor-mediated contraction of guinea pig trachea with a pA2 of 8.7. Anxiolytic in vivo.
Specifications

Chemical Identifiers

158848-32-9
414.539
5-fluoro-3-2-4-methoxy-4-r-phenylsulphinyl methyl-1-piperidinyl ethyl-1h-indole, d02ywv, r-5-fluoro-3-2-4-methoxy-4-phenylsulfinyl methyl piperidin-1-yl ethyl-1h-indole, 5-fluoro-3-2-4-methoxy-4-r-phenylsulfinyl methyl piperidin-1-yl ethyl-1h-indole, 5-fluoro-3-2-4-methoxy-4-r phenylsulfinyl methyl-1-piperidinyl ethyl-1h-indole, r-1-2-5-fluoro-1h-indol-3-yl ethyl-4-methoxy-4-phenyl-sulfinyl methyl-piperidine, 3-2-4-r-benzenesulfinyl methyl-4-methoxypiperidin-1-yl ethyl-5-fluoro-1h-indole
5-fluoro-3-[2-[4-methoxy-4-[[(R)-phenylsulfinyl]methyl]piperidin-1-yl]ethyl]-1H-indole
C23H27FN2O2S
BANYJBHWTOJQDU-GDLZYMKVSA-N
9953599
COC1(CCN(CC1)CCC2=CNC3=C2C=C(C=C3)F)CS(=O)C4=CC=CC=C4

Specifications

GR 159897
158848-32-9
5-fluoro-3-2-4-methoxy-4-r-phenylsulphinyl methyl-1-piperidinyl ethyl-1h-indole, d02ywv, r-5-fluoro-3-2-4-methoxy-4-phenylsulfinyl methyl piperidin-1-yl ethyl-1h-indole, 5-fluoro-3-2-4-methoxy-4-r-phenylsulfinyl methyl piperidin-1-yl ethyl-1h-indole, 5-fluoro-3-2-4-methoxy-4-r phenylsulfinyl methyl-1-piperidinyl ethyl-1h-indole, r-1-2-5-fluoro-1h-indol-3-yl ethyl-4-methoxy-4-phenyl-sulfinyl methyl-piperidine, 3-2-4-r-benzenesulfinyl methyl-4-methoxypiperidin-1-yl ethyl-5-fluoro-1h-indole
COC1(CCN(CC1)CCC2=CNC3=C2C=C(C=C3)F)CS(=O)C4=CC=CC=C4
414.539
414.54
10mg
C23H27FN2O2S
BANYJBHWTOJQDU-GDLZYMKVSA-N
5-fluoro-3-[2-[4-methoxy-4-[[(R)-phenylsulfinyl]methyl]piperidin-1-yl]ethyl]-1H-indole
9953599
>97%
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