GPNMB Mouse anti-Human, PE, Clone: HOST5DS, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 12-9838-42
Code : NEW
Additional Details : Weight : 0.23750kg
DescriptionA test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Tissue dissociation protocols involving enzymatic digestion should be optimized to limit proteolytic degradation of GPNMB on the cell surface. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered. The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
|PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2|
|HGFIN, NMB, glycoprotein NMB, glycoprotein nmb-like protein, osteoactivin, transmembrane glycoprotein HGFIN, transmembrane glycoprotein NMB|
|4° C, store in dark, DO NOT FREEZE!|
For Research Use Only.