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GNF 2, Tocris Bioscience™

Selective allosteric inhibitor of Bcr-Abl tyrosine kinase activity

Brand:  RD Systems (Bio-Techne) 4399/50

Code : Z1

Additional Details : Weight : 0.00010kg

Quantity 50mg

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Product Code. 13444694

  • £623.33 / 10mg

Estimated Shipment
28-06-2019

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Description

Description

Allosteric inhibitor of Bcr-Abl tyrosine kinase activity (IC50 = 267 nM); inhibits proliferation and induces apoptosis in Bcr-Abl-expressing cells. Selective for Bcr-Abl over a panel of serine, threonine and tyrosine kinases. Non-ATP-competitive.
Specifications

Chemical Identifiers

778270-11-4
374.323
gnf-2, gnf 2, 3-6-4-trifluoromethoxy phenyl amino pyrimidin-4-yl benzamide, bcr-abl inhibitor, unii-6d7q9z2w7t, 3-6-4-trifluoromethoxy phenyl amino pyrimidin-4-yl benzamide, 3-6-4-trifluoromethoxy anilino pyrimidin-4-yl benzamide, 3-6-4-trifluoromethoxy phenylamino pyrimidin-4-yl benzamide, 3-6-4-trifluoromethoxy phenyl amino-4-pyrimidinyl benzamide, 3-6-4-trifluoromethoxy-phenylamino-pyrimidin-4-yl-benzamide
3-[6-[4-(trifluoromethoxy)anilino]pyrimidin-4-yl]benzamide
C18H13F3N4O2
WEVYNIUIFUYDGI-UHFFFAOYSA-N
5311510
C1=CC(=CC(=C1)C(=O)N)C2=CC(=NC=N2)NC3=CC=C(C=C3)OC(F)(F)F

Specifications

GNF 2
778270-11-4
gnf-2, gnf 2, 3-6-4-trifluoromethoxy phenyl amino pyrimidin-4-yl benzamide, bcr-abl inhibitor, unii-6d7q9z2w7t, 3-6-4-trifluoromethoxy phenyl amino pyrimidin-4-yl benzamide, 3-6-4-trifluoromethoxy anilino pyrimidin-4-yl benzamide, 3-6-4-trifluoromethoxy phenylamino pyrimidin-4-yl benzamide, 3-6-4-trifluoromethoxy phenyl amino-4-pyrimidinyl benzamide, 3-6-4-trifluoromethoxy-phenylamino-pyrimidin-4-yl-benzamide
C1=CC(=CC(=C1)C(=O)N)C2=CC(=NC=N2)NC3=CC=C(C=C3)OC(F)(F)F
374.323
374.32
50mg
C18H13F3N4O2
WEVYNIUIFUYDGI-UHFFFAOYSA-N
3-[6-[4-(trifluoromethoxy)anilino]pyrimidin-4-yl]benzamide
5311510
>98%
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