GNB5 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Thermo Scientific PA559797

Product Code. 15797641

Description

Immunogen sequence: TFLVNVFGSC DKCFKQRALR PVFKKSQQLS YCSTCAEIMA TEGLHENETL ASLKSEAESL KGKLEEERAK LHDVELHQVA ERVEALGQFV MKTRRTLKGH GNKVLCM Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 64%.

The Gb5 protein is a G protein subunit present predomitly in the central nervous system. This protein appears to be expressed in two forms, one found in the brain of 39 kDa and one found in the retina of 44 kDa. It has also been found that Gb5 associates tightly with RGS7, a member of the superfamily of negative regulators of G protein signaling. These complexes have been localized to most regions of the brain, whereas Gb1-4 exhibit no observable colocalization with RGS7, despite their widespread codistribution throughout similar neuronal networks. This antibody is specific for a peptide sequence within the D1 blade which is not found in the Gb’s 1-4.

Specifications

• Antigen: GNB5
• Classification: Polyclonal
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O14775
• Gene Symbols: GNB5
• Immunogen: Recombit protein corresponding to Human GNB5
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry
• Conjugate: Unconjugated
• Gene: GNB5
• Gene Alias: GB5, G protein, beta subunit 5L, G protein, beta-5 subunit, gbeta5, guanine nucleotide-binding protein subunit beta-5, guanine nucleotide-binding protein, beta subunit 5L, transducin beta chain 5
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10681
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Research Use Only