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Glycoprotein VI Mouse anti-Human, eFluor 660, Clone: HY101, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 50-9813-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15500147

  • £58.09 / 25 tests


Estimated Shipment date
from Supplier 31-07-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The HY101 monoclonal antibody reacts with the glycoprotein VI (GPVI), a 62kDa type-I transmembrane glycoprotein that is expressed on mature megakaryotes and platelets. GPVI associates with the Fc receptor (FcR) gamma-chain to form a high affinity receptor for collagen. GPVI has also been reported to bind convulxin (Cvx). Phosphorylation of the ITAMs present on the FcR gamma-chain leads to recruitment of Src family kinases and activation of downstream signal transduction. GPVI has been reported to play a critical role in platelet activation and aggregation.
Description & Specifications

Specifications

Glycoprotein VI
HY101
eFluor 660
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.25μg)/test
Conjugated
GPVI, GP6
IgG1
RUO
Primary
Human