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Glucagon, Biotin, clone: ICACLS, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-9743-82

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15577366

  • £172.54 / 100µg


Estimated Shipment date
from Supplier 29-06-2018
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Description

Description

Description: This ICACLS monoclonal antibody reacts with human, mouse, and rat glucagon. Glucagon is a peptide hormone secreted by the pancreatic alpha cells found within the islets of Langerhans. Glucagon functions as an antagonist to insulin and homeostatic regulation of blood glucose levels are maintained by the critical balance between these two hormones. Glucagon acts in the liver to convert glycogen to glucose by promoting gluconeogenesis and glycogenolysis. Secretion of glucagon is stimulated by hypoglycemia, epinephrine, acetylcholine, and cholecystokinin, while secretion is inhibited by insulin and somatostatin. Abnormally high levels of glucagon are found in pancreatic tumors.Applications Reported: This ICACLS antibody has been reported for use in immunohistochemical staining, and immunohistochemical staining of formalin-fixed paraffin embedded tissue sections.Applications Tested: This ICACLS antibody has been tested by immunohistochemistry of formalin-fixed paraffin embedded tissue using low pH antigen retrieval and can be used at less than or equal to 0.5 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

Glucagon
Monoclonal
0.5mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P55095, P01275, P06883
GCG, GLP1, GLP2, GRPP
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
HumanþMurineþRat
ImmunohistochemistryþImmunohistochemistry
ICACLS
Biotin
GCG
Conjugated
Gcg
IgG1, kappa
100μg
Store at 2-8°C. Do not freeze.
Primary
2641
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