Glucagon, Alexa Fluor 488, clone: ICACLS, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 53-9743-80
Code : NEW
Additional Details : Weight : 0.09500kg
DescriptionDescription: This ICACLS monoclonal antibody reacts with human, mouse, and rat glucagon. Glucagon is a peptide hormone secreted by the pancreatic alpha cells found within the islets of Langerhans. Glucagon functions as an antagonist to insulin and homeostatic regulation of blood glucose levels are maintained by the critical balance between these two hormones. Glucagon acts in the liver to convert glycogen to glucose by promoting gluconeogenesis and glycogenolysis. Secretion of glucagon is stimulated by hypoglycemia, epinephrine, acetylcholine, and cholecystokinin, while secretion is inhibited by insulin and somatostatin. Abnormally high levels of glucagon are found in pancreatic tumors.Applications Reported: This ICACLS antibody has been reported for use in immunohistochemical staining, and immunohistochemical staining of formalin-fixed paraffin embedded tissue sections.Applications Tested: This ICACLS antibody has been tested by immunohistochemistry of formalin-fixed paraffin embedded human tissue using low pH antigen retrieval and can be used at less than or equal to 10 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser.Filtration: 0.2μm post-manufacturing filtered.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|P01275, P06883, P55095|
|GCG, GLP1, GLP2, GRPP|
|Alexa Fluor 488|
|Store at 2-8°C. Do not freeze. Light-sensitive material.|
For Research Use Only.