Gibco™ IL33 Recombinant Human Protein

Recombinant IL33 is a bioactive protein intended for use in cell culture applications

Brand: Gibco™

Manufacturer Part Number: PHC9254

UNSPSC: 12352202

Code: 50

Additional Details:
Additional Details: Weight: 0.99000kg

Disclaimers: For Research Use Only. Not for use in diagnostic procedures.

Product Code. 10309119

Quantity Price
1 £ 86.75 / Each
Estimated Shipment date
from Supplier 04-05-2017
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For Research Use Only. All usage must comply with product instructions.

Description and Specification


Storage Requirements Lyophilized Human IL-33 should be stored at 2° to 8°C, preferably desiccated. Store reconstituted Human IL-33 at ≤ -20°C. Avoid freeze/thaw cycles.
Cross Reactivity Human
Without Additives Carrier Protein
Source Human
Purity 95%
Gene Alias IL-33
Validated Application Cell Culture
Gene Symbol IL33
Specific Reactivity 1.0 x 107 - 1.0 x 106 units/mg
Gene ID (Entrez) 90865
For Use With (Application) Cell Culture; Mammalian Cell Culture
Protein Subtype Interleukins
Accession Number NM_033439
Molecular Weight 18kDa
Biological Activity ED50 range: 0.1 to 1.0ng/mL
Assays Proliferation of Mouse D10S Cells
Purification Method Sequential Chromatography
Structural Form Recombinant/Ligand
Endotoxin Concentration <0.1ng/μg
Quantity 10μg
Protein Family Cytokines & Receptors
Expression System E. coli
Protein Length 159 aa
Format Lyophilized

IL33 is a proinflammatory cytokine with structural homology similar with IL-1 family cytokines. IL33 exerts its biological effects by binding to the receptor ST2 and forming a complex with IL-1 Receptor Accessory Protein. Intracellular proteins within in the NFκB and MAP kinase signaling pathways are activated leading to the production of the type 2 cytokines IL-5 from polarized TH2 cells.

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