Gibco™ IL33 Recombinant Human Protein

Recombinant IL33 is a bioactive protein intended for use in cell culture applications

Overview
Brand: Gibco™

Manufacturer Part Number: PHC9251

UNSPSC: 12352202

Code: 50

Additional Details:
Additional Details: Weight: 0.00010kg



Disclaimers: For Research Use Only. Not for use in diagnostic procedures.

Product Code. 10359004

Quantity Price
1 £ 984.0 / Each
Estimated Shipment date
from Supplier 12-05-2017
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For Research Use Only. All usage must comply with product instructions.
 

Description and Specification

Specification

Validated Application Cell Culture
Expression System E. coli
Protein Length 159 aa
Molecular Weight 18kDa
Protein Subtype Interleukins
Accession Number NM_033439
Endotoxin Concentration <0.1ng/μg
Gene ID (Entrez) 90865
Protein Family Cytokines & Receptors
Cross Reactivity Human
Specific Reactivity 1.0 x 107 - 1.0 x 106 units/mg
Source Human
Purity 95%
Structural Form Recombinant/Ligand
Without Additives Carrier Protein
Quantity 100μg
Assays Proliferation of Mouse D10S Cells
Biological Activity ED50 range: 0.1 to 1.0ng/mL
Purification Method Sequential Chromatography
Gene Symbol IL33
Format Lyophilized
Storage Requirements Lyophilized Human IL-33 should be stored at 2° to 8°C, preferably desiccated. Store reconstituted Human IL-33 at ≤ -20°C. Avoid freeze/thaw cycles.
Gene Alias IL-33
For Use With (Application) Cell Culture; Mammalian Cell Culture

IL33 is a proinflammatory cytokine with structural homology similar with IL-1 family cytokines. IL33 exerts its biological effects by binding to the receptor ST2 and forming a complex with IL-1 Receptor Accessory Protein. Intracellular proteins within in the NFκB and MAP kinase signaling pathways are activated leading to the production of the type 2 cytokines IL-5 from polarized TH2 cells.

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