Gibco™ IL33 Recombinant Human Protein

Recombinant IL33 is a bioactive protein intended for use in cell culture applications

Overview
Brand: Gibco™

Manufacturer Part Number: PHC9251

100 UG IL-33 RECOMBINANT HUMAN 100µG STORE AT 4°C

UNSPSC: 12352202

Code: 50

Additional Details:
Additional Details: Weight: 0.00010kg



Disclaimers: For Research Use Only. Not for use in diagnostic procedures.

Product Code. 10359004

Quantity Price
1 £ 984.0 / Each
Estimated Shipment date
from Supplier 07-12-2016
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For Research Use Only. All usage must comply with product instructions.
 

Description and Specification

Specification

Accession Number NM_033439
Cross Reactivity Human
For Use With (Application) Cell Culture; Mammalian Cell Culture
Format Lyophilized
Gene ID (Entrez) 90865
Molecular Weight 18kDa
Purification Method Sequential Chromatography
Purity 95%
Quantity 100μg
Source Human
Storage Requirements Lyophilized Human IL-33 should be stored at 2° to 8°C, preferably desiccated. Store reconstituted Human IL-33 at ≤ -20°C. Avoid freeze/thaw cycles.
Without Additives Carrier Protein
Structural Form Recombinant/Ligand
Protein Subtype Interleukins
Endotoxin Concentration <0.1ng/μg
Gene Alias IL-33
Gene Symbol IL33
Assays Proliferation of Mouse D10S Cells
Validated Application Cell Culture
Protein Family Cytokines & Receptors
Expression System E. coli
Protein Length 159 aa
Biological Activity ED50 range: 0.1 to 1.0ng/mL
Specific Reactivity 1.0 x 107 - 1.0 x 106 units/mg

IL33 is a proinflammatory cytokine with structural homology similar with IL-1 family cytokines. IL33 exerts its biological effects by binding to the receptor ST2 and forming a complex with IL-1 Receptor Accessory Protein. Intracellular proteins within in the NFκB and MAP kinase signaling pathways are activated leading to the production of the type 2 cytokines IL-5 from polarized TH2 cells.

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