Collagenase, Type I, Powder

Cleaves bond between neutral amino acid (X) and glycine in sequence Pro-X-Gly-Pro, which is found with high frequency in collagen

Brand: Gibco

Manufacturer Part Number: 17018029


UNSPSC: 41122100

Code: 50

Additional Details:
Additional Details: Weight: 0.01000kg

Product Code. 11500536

Quantity Price
1 £ 94.25 / 500mg
EU Stock 44
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For Research Use Only. All usage must comply with product instructions.

Description and Specification


Quantity 500 mg
Storage Requirements Storage: 2°C to 8°C. Protect from light. Shelf life: 24 months from date of manufacture
With Additives No Phenol Red

Collagenase is unique among proteases in its ability to degrade the triple-helical native collagen fibrils commonly found in connective tissues such as skin, tendon, blood vessels, and bone. Collagenase disaggregation is suitable for the culture of human tumors, mouse kidney, human adult and fetal brain, and many other tissues including epithelium. Collagenase is relatively gentle, dissociates well at physiological temperature and pH, and requires no mechanical agitation or special equipment.

  • Isolated from Clostridium histolyticum.
  • Packaged as lyophilized, non-sterile powder for research use in cell or tissue dissociation, and organ perfusions
  • Activity is >125 units/mg
  • Contains average levels of collagenase, caseinase, clostripain, and tryptic activities, and is well-suited for digestion of fat, adrenal, and liver cells or tissues

Cell Culture, Mammalian Cell Culture