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Gemcitabine hydrochloride, Tocris Bioscience™

DNA synthesis inhibitor

Brand:  Tocris (Bio-Techne) 325950

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13432674

  • £460.11 / 50mg

Estimated Shipment date
from Supplier 01-04-2020

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Description

Description

Deoxycytidine analog that inhibits DNA synthesis. Metabolized to form gemcitabine triphosphate (dFdCTP) and gemcitabine diphosphate (dFdCDP). dFdCTD inhibits ribonucleotide reductase causing a reduction in cellular nucleotides. dFdCTP is incorporated in DNA resulting in DNA strand termination. Displays antitumor activity in vitro and in vivo.
Specifications

Chemical Identifiers

122111-03-9
299.659
gemcitabine hcl, 2',2'-difluorodeoxycytidine monohydrochloride, 2'-deoxy-2',2'-difluorocytidine hydrochloride, 2 1h-pyrimidinone, 4-amino-1-2-deoxy-2,2-difluoro-d-erythro-pentofuranosyl
CHEBI:31647
[H+].C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F.[Cl-]
C9H12ClF2N3O4
OKKDEIYWILRZIA-OSZBKLCCSA-N
44558863
4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one;hydron;chloride

Specifications

Gemcitabine hydrochloride
122111-03-9
gemcitabine hcl, 2',2'-difluorodeoxycytidine monohydrochloride, 2'-deoxy-2',2'-difluorocytidine hydrochloride, 2 1h-pyrimidinone, 4-amino-1-2-deoxy-2,2-difluoro-d-erythro-pentofuranosyl
[H+].C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F.[Cl-]
299.659
CHEBI:31647
>99%
50mg
C9H12ClF2N3O4
OKKDEIYWILRZIA-OSZBKLCCSA-N
4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one;hydron;chloride
44558863
299.66
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