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GE Healthcare Sepharose™ Fast Flow Cation Exchange Media

Used for preparative protein separations in both research and industrial applications. GE Healthcare CM Sepharose™ Fast Flow Cation Exchange Media is composed of crosslinked 6% agarose beads, with carboxymethyl (CM) weak cation exchange groups.

Brand:  GE Healthcare 17-0719-01

UNSPSC : 41104018

Code : GE

Additional Details : Weight : 1.58760kg

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Product Code. 10714592

  • £405.30 / 500mL


Estimated Shipment
12-09-2017
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Description

Description

  • Hydrophilic nature of base matrix ensures low levels of non-specific binding leading to low levels of host cell-derived impurities in the elution pool
  • Composed of crosslinked 6% agarose beads
  • Reproducible
  • Part of Sepharose Fast Flow ion exchange platform
  • High chemical stability, allowing well proven cleaning-in-place (CIP) and sanitization protocols
  • Available in range of pre-packed process development tools

SP Sepharose:

  • Ligand: Sulphopropyl
  • Ion Exchanger Type: Strong cation exchanger
  • Ionic Capacity: 0.18 to 0.25mmol H+/mL medium
  • Binding capacity: 70mg ribonuclease A/mL medium
CM Sepharose:
  • Ligand: Carboxymethyl
  • Ion Exchanger Type: Weak cation exchanger
  • Ionic Capacity: 0.09 to 0.13mmol Hl+/mL medium
  • Binding capacity: 50mg ribonuclease A/mL medium

Used extensively for capture and intermediate purification of wide range of approved biopharmaceuticals

Specifications

Specifications

0.09 to 0.13mM Hl+/mL
50mg Ribonuclease A/mL medium
For preparative Protein separations in research and industrial appliCatIons, for capture and intermediate purifiCatIon of wide range of approved biopharmaceuticals
6% Cross-Linked Agarose
500mL
Stable in commonly used aqueous Buffers: 1M NaOH, 8M Urea, 8M Guanidine Hydrochloride, 70% Ethanol
4 to 30°C
CM Sepharose fast flow media
Weak CatIon Exchanger
300 to 600cm/Hour
Carboxymethyl
100kPa
500mL
20% Ethanol
45 to 165μm
4 to 13