GE Healthcare Dharmacon siGLO™ Lamin A/C Control siRNA (Human)

Silences the human Lamin A/C gene and is labeled with DY-547

Overview
Brand: GE Healthcare Dharmacon

Manufacturer Part Number: D-001620-03-20

SIGLO LAMINA/C SIR(MO) 20NMOL

UNSPSC: 41106402

Code: P1

Additional Details:
Additional Details: Weight: 0.01000kg



Product Code. 11507220

Quantity Price
1 £ 479.52 / 20nmol
Estimated Shipment date
from Supplier 16-12-2016
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Description and Specification

Specification

Accession Number NM_019390
Fluorophore Cy3 Rhodamine or Polyethylene
For Use With (Application) RNAi experiments in Mouse cells, significantly extend siRNA stability and Fluorescence compared to conventional siRNAs similarly labeled with fluorophores
Product Type Lamin A/C siRNA - Mouse
Quantity 20nmol

Lamins are intermediate filament-type proteins, which form major components of nuclear lamina. Lamins A and C have close sequence homology and are derived by differential splicing and alternative polyadenylation from one gene. This gene is abundantly expressed in most cells, and because it is non-essential, knockdown of the corresponding mRNA does not affect cell viability.

  • Targets accession numbers: NM_005572, NM_170707, NM_170708 (Human)
  • Labeled with DY-547
  • Absorbance/Emission Max is 557/570nm
  • A Cy3, Rhodamine or PE filter can be used
  • Significantly extended intensity of the fluorescence signal (7 days or longer)
  • Positive correlation of fluorescence with transfection efficiency and target gene silencing

  • Stable, fluorescent positive control suitable for RNAi experiments in human cells
  • Control siRNA is chemically modified to significantly extend siRNA stability and fluorescence compared to conventional siRNAs similarly labeled with fluorophores