Link the activity of a microRNA mimic to post-transcriptional regulation of its putative gene target, measure modulation of endogenous Aldolase A mRNA levels
The miRIDIAN microRNA Mimic Endogenous Positive Control provides the ability to monitor effects of a specific mimic on target protein levels in a validated endogenous assay. The assay is based upon the targeted activity of miR-122 on Aldolase A mRNA levels in cell lines that express low to moderate levels of miR-122.
Validated miRIDIAN microRNA Mimic that targets Aldolase A in human, mouse and rat
Provides the ability to optimize assay conditions by monitoring mimic function on an endogenous gene target (Aldolase A) with a conserved miR-122 binding sit