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Tocris Bioscience™ GBR 12909 dihydrochloride

Selective DA uptake inhibitor; also σ ligand

Brand:  Tocris Bioscience™ 042110

Code : Z1

Additional Details : Weight : 0.01000kg

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Product Code. 13447633

  • £95.55 / 10mg

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Description

Description

Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration.
Specifications

Specifications

1-[2-[Bis-(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride
>98%
Observed MW: 523.49
Soluble to 50mM in DMSO
67469-78-7
C28H32F2N2O.2HCl
10mg
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