Gata-4 Rat anti-Human, Mouse, Clone: eBioEvan, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9980-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15228307

Quantity Price
1 £ 146.13 / 100µg
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Gene Alias Gata4
Quantity 100μg
Antigen Gata-4
Monoclonal or Polyclonal Monoclonal
Clone eBioEvan
Format Purified
Primary or Secondary Primary
Regulatory Status RUO
Isotype IgG2a
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Species Reactivity Human, Mouse
Concentration 0.5mg/mL
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Western Blotting
Conjugate Unlabeled
Host Species Rat
Storage Requirements Store at 2-8°C.

The eBioEvan monoclonal antibody reacts with mouse and human Gata-4. In a western blot of C57Bl/6 and BALB/c mouse heart lysates, a single band is present, suggesting that this antibody does not cross-react with Gata-5 or Gata-6, which are also expressed in the heart, but with different molecular weights. The eBioEvan monoclonal antibody has been successfully used in flow cytometry on HEK 293T cells transiently transfected with either mouse Gata-4 or human Gata-4.

Gata-4 is a member of the GATA family of transcription factors, which are characterized by a conserved DNA binding domain containing two zinc fingers. The mouse Gata-4 gene encodes a protein of 48kDa. Studies show that Gata-4 plays an important role in controlling cardiomyocyte differentiation, proliferation and survival. Gata-4 is expressed during fetal development, as well as in the adult mouse heart. It also appears to modulate gene expression in the gut, liver, and gonads.